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Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract: TFPI is expressed by endothelial and smooth muscle cells in the vasculature.However, the role of endogenous TFPI in vascular smooth muscle cells (VSMCs) in thrombosis and vascularTFPI concentration was also detected in the TFPITie2 (mice deleted TFPI in endothelial cellsand cells of hematopoietic origin) mice.

Keywords： arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth musclecells    

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Effect of bradykinin on bradykinin-B2 receptor in rat aortic vascular smooth muscle cells and the involved

Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 225-228 doi: 10.1007/s11684-010-0003-z

Abstract: bradykinin-B2 receptor as well as the possible involved signal transduction pathways in cultured rat aortic vascularsmooth muscle cells (VSMCs).Cells after 4–6 passages were used in the experiment.

Keywords： bradykinin     vascular smooth muscle cells     signal transduction pathways    

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Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 323-331 doi: 10.1007/s11684-008-0062-6

Abstract: Hypertension is characterized by vascular smooth muscle constriction and vascular remodeling involvingmuscle functions.Evidence for the role of CAS in the regulation of vascular smooth muscle contractility is presented.Contraction stimulation induces CAS phosphorylation on Tyr-410 in arterial smooth muscle, creating theThese new findings establish the important role of CAS in the modulation of vascular smooth muscle functions

Keywords： Contraction stimulation     phosphatase-proline     molecular structure     discovered     hypertension    

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sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascularsmooth muscle cells

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 320-329 doi: 10.1007/s11684-016-0463-x

Abstract: Rat aortic vascular smooth muscle cells (VSMCs) were treated with phosphate buffer solution or 500 µ

Keywords： p-cresyl sulfate     atherosclerosis     plaque stability     vascular smooth muscle cell    

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Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 177-180 doi: 10.1007/s11684-009-0021-x

Abstract: To evaluate the mechanism of vascular endothelial growth factor (VEGF) on the prevention of restenosisangioplasty, the recombinant adenovirus vector containing hVEGF cDNA was constructed and transfected into vascularsmooth muscle cells (VSMC) .Then, the VSMC and human umbilical vein endothelial cells (HUVEC) were divided into control group, H

Keywords： vascular endothelial growth factors     restenosis     reactive oxygen species     endothelial cells     vascular smoothmuscle cell    

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Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Engineering doi: 10.1016/j.eng.2023.06.009

Abstract: Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause.cyclase (sGC)–3′,5′-cyclic guanosine monophosphate (cGMP)–protein kinase G (PKG) signaling pathway in vascularsmooth muscle cells (VSMCs) to dilate the arteries.These effects were eliminated by pre-incubating vascular rings with the sGC inhibitors NS 2028 or ODQsmooth muscle cells (MOVAs).

Keywords： Myocardial ischemia     Vasomotion     Soluble guanylate cyclase     Buxu Tongyu Granule    

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Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 398-400 doi: 10.1007/s11684-007-0077-4

Abstract: relationship between the expression of adrenomedullin (ADM) and microvessel density (MVD) and prognosis in smoothmuscle tumor of uterus.The ADM is an important angiogenic factor in smooth muscle tumor of uterus.

Keywords： anticarcinogenic     microvessel density     malignant potency     muscle     uterine leiomyosarcoma    

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Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 284-286 doi: 10.1007/s11684-009-0062-1

Abstract: To evaluate the role of nitric oxide in the biological effects of vascular endothelial growth factor(VEGF) and the possible mechanism of VEGF, the cultured vascular endothelial cells of rabbit aorta wereThe absorbance () value of vascular endothelial cells and the levels of prostaglandin (PGI), endothelinendothelial cells and that L-NAME could inhibit the effect of VEGF partially.endothelial cells by VEGF.

Keywords： vascular endothelial growth factor     nitric oxide     N-nitro-L-arginine methyl ester     vascular endothelialcells    

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Pluripotent stem cells exhibiting similar characteristics can be isolated from human fetal bone marrow, heart, liver, muscle, lung, derma, kidney, and fat

FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 185-191 doi: 10.1007/s11684-007-0035-1

Abstract: population derived from human fetal bone marrow (BM), termed here Flk1CD34 postembryonic pluripotent stem cellsIn this study, we further isolated pluripotent stem cells from human fetal heart, liver, muscle, lung, derma, kidney, and fat and then analyzed the characteristics and function of these stem cells.Morphologically, these cells were fibroblast-like and the doubling time was about 30 h.cells and hepatocytes.

Keywords： endothelial     phenomenon     ectodermal     Flk1CD34 postembryonic     irradiated non-obese    

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Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 421-430 doi: 10.1007/s11684-015-0424-9

Abstract: mucin-type O-glycoprotein expressed in diverse cell types, such as lymphatic endothelial cells(LECs) in the vascular system and fibroblastic reticular cells (FRCs) in lymph nodes.In the vascular system, normal expression of PDPN at the LEC surface requires transcriptional activationThis review provides a comprehensive overview of the roles of PDPN in vascular development and lymphoid

Keywords： podoplanin     CLEC-2     Prox1     O-glycosylation     lymphatic vascular development and maintenance     lymphoid    

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included in a bicistronic vector enhances and stabilizes follistatin gene expressions in both transgenic cells

Xiaoming HU,Jing GUO,Chunling BAI,Zhuying WEI,Li GAO,Tingmao HU,Shorgan BOU,Guangpeng LI

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 87-96 doi: 10.15302/J-FASE-2016087

Abstract: pMAR-CAG-FST-IRES-AcGFP1-polyA-MAR (pMAR-FST) vector had higher capacity to form monoclonal transgenic cellsRemarkably, protein expression in transgenic cells with the pMAR-FST vector was significantly higherTotal muscle growth in F mice was significantly greater than in wild-type mice, with larger musclesdevelopment and the trend of muscle growth.resistant genes and frame structure, enhances and stabilizes gene expressions in both transfected cells

Keywords： safety of transgenic     bicistron gene transfer body     transgenic mice     muscle development    

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Extended model predictive control scheme for smooth path following of autonomous vehicles

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 1,   Pages 4-4 doi: 10.1007/s11465-021-0660-4

Abstract: extended MPC method solved by differential evolution optimization algorithm is proposed to realize optimal smoothResults indicate that the proposed method can obtain the smooth transition to follow the optimal drivable

Keywords： autonomous vehicles     vehicle dynamic modeling     model predictive control     path following     optimization algorithm    

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Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering

Shiying Li, Tianmei Qian, Xinghui Wang, Jie Liu, Xiaosong Gu

Engineering 2017, Volume 3, Issue 1,   Pages 3-15 doi: 10.1016/J.ENG.2017.01.005

Abstract: ncRNAs that are related to tissue engineering for the repair and regeneration of nerve, skin, liver, vascularsystem, and muscle tissue; to discuss their regulation and delivery; and to anticipate their potential

Keywords： Tissue engineering     Noncoding RNAs     MicroRNAs     Nerve     Skin     Liver     Vascular system     Muscle    

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Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with non-muscle invasive bladder

Jiangang Pan,Mo Liu,Xing Zhou

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 241-249 doi: 10.1007/s11684-014-0328-0

Abstract:

Approximately 70% of newly diagnosed bladder tumors are non-muscle invasive bladder cancer (NMIBC)

Keywords： non-muscle invasive bladder cancer     bacillus Calmette-Guérin (BCG)     meta-analysis    

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Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 67-78 doi: 10.1007/s11684-012-0176-8

Abstract: oxygen supplies creates a hypoxic and acidic microenvironment in the tumor tissues, which fosters tumor cellsHowever, current tumor vascular normalizing drugs display moderate anticancer efficacy.Accumulated data have shown that a variety of vasculogenic/angiogenic tumor cells and genes play importantTherefore, multiple-targeting of vasculogenic tumor cells and genes may improve the efficacy of tumorvascular normalization.

Keywords： angiogenesis     vasculogenesis     neovascularization     tumor     vasculature     normalization     traditional Chinese medicine    

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Title Author Date Type Operation

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

Effect of bradykinin on bradykinin-B2 receptor in rat aortic vascular smooth muscle cells and the involved

Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,

Journal Article

Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Journal Article

sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascularsmooth muscle cells

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Journal Article

Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Journal Article

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Journal Article

Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Journal Article

Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Journal Article

Pluripotent stem cells exhibiting similar characteristics can be isolated from human fetal bone marrow, heart, liver, muscle, lung, derma, kidney, and fat

FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia

Journal Article

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Journal Article

included in a bicistronic vector enhances and stabilizes follistatin gene expressions in both transgenic cells

Xiaoming HU,Jing GUO,Chunling BAI,Zhuying WEI,Li GAO,Tingmao HU,Shorgan BOU,Guangpeng LI

Journal Article

Extended model predictive control scheme for smooth path following of autonomous vehicles

Journal Article

Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering

Shiying Li, Tianmei Qian, Xinghui Wang, Jie Liu, Xiaosong Gu

Journal Article

Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with non-muscle invasive bladder

Jiangang Pan,Mo Liu,Xing Zhou

Journal Article

Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Journal Article